
姓名:马燕
教授、中药学博士生导师、药剂学硕士生导师
简介:
广东省科技专家库专家
广东省高层次人才评审专家
广州市科技专家库专家
国家自然科学基金评审专家
教育经历
[1]2003.09-2006.06 沈阳药科大学-博士
[2]2000.09-2003.06 沈阳药科大学-硕士
[3]1996.09-2000.06 沈阳药科大学-学士
工作经历
[1]2017.01-至今,新葡的京集团35222vip-教授
[2] 2010.01-2016.12,新葡的京集团35222vip-副教授
[3] 2012.12-2013.12,美国北卡罗来纳大学(教堂山)-访问学者
[4]2006.07-2009.12,新葡的京集团35222vip-讲师
研究方向:聚焦于药物新剂型与递送系统的设计,并深入探究其与药物体内吸收规律及药效发挥之间的内在关联。
研究领域:新型靶向递药系统的研究
联系方式:mayan2006@gzucm.edu.cn
研究课题
[1]单硫醚键介导的氧化还原敏感性多西他赛-亚油酸前药自组装纳米粒的开发,广州市科技计划项目,20万, 2019/04-2021/03,结题,主持。
[2]一种制备方法简单的刺激响应型双功能复合纳米药物制剂的研究,广东省科技计划项目,2016/06-2019/05,30万,结题,主持。
[3]基于改善难溶性药物及其制剂口服生物利用度的新技术研究,广东省科技计划项目,2015/06-2018/05,20万,结题,主持。
[4]多功能鸦胆子油分子配型组装纳米乳逆转肿瘤多药耐药的研究,国家自然科学基金项目,2015/01-2017/12,23万元,结题,主持。
[5]复方紫杉醇多功能纳米给药系统靶向逆转肿瘤多药耐药性的研究,广东省医学科学技术研究基金项目,2015/07-2017/06,0.5万,结题,主持。
[6]新葡的京集团35222vip“青年英才培养工程”,2015/01-2018/12,20万,结题,主持。
[7]多功能分子配型组装纳米给药系统抗肿瘤分子机制的研究,新葡的京集团35222vip“薪火计划”项目,2014/11-2016/12,5万,结题,主持。
主编或参编教材及著作
[1]《中药药剂学》,科学出版社,副主编
[2]《药用高分子材料学》,中国中医药出版社,编委
[3]《药剂学》,中国中医药出版社,编委
代表性论文论著
[1] Xiaofeng Guo, Shuni Zeng, Qiwei Chen, et. al. Brucea javanica-derived natural lipid droplets: selective oral lymph targeting and endocytic transport mechanisms, Pharmaceutics, 2026, 18(2): 260.(唯一通讯作者)
[2] Xiaofeng Guo, Shuni Zeng, Qiaoyu Huang, et. al. Lipid Droplet-Mediated Extraction of Perilla Seed Oil: Stability, Absorbability and Carrier Potential. Lipids, 2025, 60(6):481-490.(唯一通讯作者)
[3] Quandong Li, Xinru Chen, Wen Lin, et. al. Application of a novel multicomponent nanoemulsion to tumor therapy Based on the theory of “unification of drugs and excipients”. Pharmaceutical Development and Technology, 2023, 28 (3-4):351-362.(唯一通讯作者)
[4] Xinru Chen, Quandong Li, Zipeng Huang, et. al. Construction and evaluation of curcumin upconversion nanocarriers decorated with MnO2 for tumor photodynamic therapy. Drug Delivery and Translational Research, 2022, 12(11):2678-2692.(唯一通讯作者)
[5] Zipeng Huang, Xinru Chen, Ying Li, et. al. Excogitation and assessment of curcumin-vitamin E self-assembly PEGylated nanoparticles by the route of oral administration. Journal of Pharmaceutical Sciences, 2021, 110 (1): 146-154.(共同通讯作者)
[6] Yan Ma, Liuting Zhong, Zhuo Peng, et. al. Development of a highly water-soluble lycopene cyclodextrin ternary formulation by the integrated experimental and modeling techniques. AAPS PharmaSciTech, 2020, 22 (1):5.(共同第一作者)
[7] Yan Ma, DongYang Zhang, Zhuo Peng, et. al. Delivery of Platinum (IV) prodrugs via Bi2Te3 nanoparticles for photothermal-chemotherapy and photothermal/photoacoustic imaging. Molecular Pharmaceutics, 2020, 17(12):3403-3411. (共同第一作者)
[8] Ying Li, Pei Xiao, Zipeng Huang, et. al. Evaluation of curcumin-mediated photodynamic therapy on the reverse of multidrug resistance in tumor cells. RSC Advances, 2020, 10:298-306. (共同通讯作者)
[9] Junqiu Zhai, Qingguo Li, Huahua Xu, et. al. An aseptic one-shot bottom-up method to produce progesterone nanocrystals: controlled size and improved bioavailability. Molecular Pharmaceutics, 2019, 16 (12):5076-5084. (共同通讯作者)
[10] Xia Yan, Shuqing Cao, Ying Li, et. al. Internalization and subcellular transport mechanisms of different curcumin loaded nanocarriers across Caco-2 cell model. Journal of Drug Delivery Science and Technology, 2019, 52: 660-669. (共同通讯作者)
[11] Shuqing Cao, Kuanyun Zhang, Xia Yan, et. al. Preparation and evaluation of Paclitaxel and Brucea Javanica oil core-matched nanoemulsions to treat cancer in vitro and in vivo, Chinese Herbal Medicines, 2018, 10(3): 310-317.(唯一通讯作者)
[12] Yan Ma, Dan Liu, Dun wang, et. al. Combinational delivery of Hydrophobic and Hydrophilic Anticancer Drugs in Single Nanoemulsions to Treat MDR in Cancer,Molecular Pharmaceutics,2014, 11:2623-2630(共同第一作者)
其他代表性业绩
无